Listening to this cast the main thing that struck me was how it is pretty much opposite to the advice I received when I was at university. I'm not saying totally opposite but certainly the focus was different.
The cast could, as I understand it, be summed up as "The number 1 priority is to come out with a good GPA/award, everything else is secondary."
When I was at uni, 1989-93, the message was quite different. I wasn't told "Don't worry about your grades, they don't mean anything" but grades were not represented as the #1 priority. The message was much more "So long as you at least get a degree that's fine, it's the extra curricular activities that employers are more interested in." This was the message I got from my 6th form (6th form is an optional end of secondary/pre-tertiary education where you study A-Levels, pretty much a requirement for getting into university) college careers service, my university careers service, the employment services office (Job Centre), the media and employers I spoke to. Even my bank sent me a booklet saying "Congratulations on getting into university, here's what we look for in our graduate recruits..." and giving similar advice. The view was that there are loads of graduates coming out each year with the same or similar degree as you, you need lots of good extra-curriculars to demonstrate your unique selling point, the thing that makes you different from all the rest. Indeed it was only the 'crusty old academics' (normally derided for giving poor careers advice) who seemed worried about grades.
I graduated with a II:ii (aka a 'Desmond') in Biochemistry from University of Keele in 1993 (along with subsidiary degrees in Computer Science, Engineering Math and Economics). I don't know that I've ever been ruled out of a job on the basis of the class of my degree. I do know that I've very rarely been asked what class degree I got, I know a lot of people who graduated around the same time as me with II:i and Firsts but had as much or more trouble than me finding graduate jobs and employers seemed much more interested in the fact that I'd been Treasurer of the Scottish society for a year, a member of the Constitutional Committee for 3 years and had raised over £100,000 pounds for charity over 3 years as a very active member of the RAG committee than what my grades were.
Presumably things have changed in the intervening 15 years.