How can one spot potential psychopaths during an interview? Psychopaths are able to effectively blend into the surroundings, but can have devastating consequences to work relationships and affect the work environment (not to mention the relationships at home. They are often characterized by appearing to interact with their colleagues, but really relying on subterfuge, lies and cheating to achieve their ends. They feel that they are always right, even if they lie to achieve their own ends. Giving impressive answers to normal interview questions would be no problem for the average psychopath. Once identified it is usually very problematic to deal with employees that are psychopaths, or to remove them from their positions. Screening them out during the interview process would always be preferable.